{"v":1,"ledgerId":"octocrylene","generatedAt":"2026-11-05T21:33:31.523Z","query":"(TITLE:(\"Octocrylene\" OR \"OCTOCRYLENE\" OR \"2-ETHYLHEXYL 2-CYANO-3,3-DIPHENYLACRYLATE\" OR \"6197-30-4\") OR ABSTRACT:(\"Octocrylene\" OR \"OCTOCRYLENE\" OR \"2-ETHYLHEXYL 2-CYANO-3,3-DIPHENYLACRYLATE\" OR \"6197-30-4\")) AND (TOXICITY OR EXPOSURE OR \"ENDOCRINE\" OR \"REPRODUCTIVE\" OR CARCINOGEN* OR \"BIOMONITORING\" OR \"SYSTEMATIC REVIEW\") AND SRC:MED AND LANG:eng","totalPapers":208,"lastYearPapers":28,"analysed":37,"byFunding":{"independent":16,"industry":2,"mixed":0,"none_declared":0,"unclear":19},"byDesign":{"human":3,"animal":12,"in_vitro":8,"review":1,"other":13},"byFinding":{"concern":20,"no_effect":14,"mixed":3},"gap":{"independent":{"concern":10,"total":16},"industry":{"concern":0,"total":2}},"fundingSources":{"full_text":5,"grant_metadata":20,"abstract":0,"none":12},"newestPublished":"2026-11-03","papers":[{"id":"pmid:42958843","pmid":"42958843","pmcid":"","doi":"10.1080/15376516.2026.2755745","title":"Integrated genotoxic, developmental, and <i>in-silico</i> assessment of organic UV-filters Octocrylene and Homosalate in <i>Drosophila melanogaster</i>.","journal":"Toxicology mechanisms and methods","published":"2026-11-03","design":"animal","finding":"concern","summary":"Octocrylene induced dose-dependent genotoxicity, developmental impairment, and demonstrated binding affinity to EGFR and Eip75B in Drosophila melanogaster.","funding":"unclear","conflictOfInterest":false,"fundingEvidence":[],"fundingSource":"none","verified":false},{"id":"pmid:42966287","pmid":"42966287","pmcid":"","doi":"10.1016/j.ecoenv.2026.120987","title":"Co-exposure to octocrylene and polystyrene nanoplastics induces neuro- and reproductive toxicity in zebrafish: Association with circadian rhythm and HPG axis disruption.","journal":"Ecotoxicology and environmental safety","published":"2026-10-31","design":"animal","finding":"concern","summary":"Co-exposure of adult zebrafish to octocrylene and polystyrene nanoplastics for 28 days disrupted circadian clock genes and the HPG axis, causing neurotoxicity and reproductive impairment.","funding":"unclear","conflictOfInterest":false,"fundingEvidence":[],"fundingSource":"none","verified":false},{"id":"pmid:42810470","pmid":"42810470","pmcid":"","doi":"10.1016/j.etap.2026.105180","title":"Environmental presence and toxicological risks of octocrylene in the marine, coastal and transition ecosystems.","journal":"Environmental toxicology and pharmacology","published":"2026-09-29","design":"other","finding":"concern","summary":"A review of octocrylene indicates environmental presence across aquatic ecosystems and toxicological risks across 14 taxonomic groups, suggesting impacted coastal areas are a priority concern.","funding":"unclear","conflictOfInterest":false,"fundingEvidence":[],"fundingSource":"none","verified":false},{"id":"pmid:42705437","pmid":"42705437","pmcid":"","doi":"10.1016/j.envres.2026.125631","title":"Emerging contaminants and legacy pollutants exhibit contrasting exposure and hazard patterns in sediments and suspended particulate matter from an Antarctic coastal ecosystem.","journal":"Environmental research","published":"2026-09-07","design":"other","finding":"concern","summary":"Analysis of Antarctic coastal samples showed triclosan was detected in suspended particulate matter and drove immediate ecological risk with a risk quotient greater than one.","funding":"unclear","conflictOfInterest":false,"fundingEvidence":[],"fundingSource":"none","verified":false},{"id":"pmid:42916227","pmid":"42916227","pmcid":"PMC13614191","doi":"10.1021/acs.est.6c09445","title":"Assessing UV Filter Exposure in Queensland, Australia: Human Biomonitoring Evidence Highlighting Homosalate in Children.","journal":"Environmental science & technology","published":"2026-09-01","design":"human_cross_sectional","finding":"no_effect","summary":"Biomonitoring of pooled urine samples in Australia from 2012 to 2023 showed octocrylene biomarker levels increased over time and were highest in children.","funding":"unclear","conflictOfInterest":false,"fundingEvidence":[],"fundingSource":"none","verified":false},{"id":"pmid:42508666","pmid":"42508666","pmcid":"","doi":"10.1016/j.biortech.2026.135514","title":"Chronic toxicity of triazine-based and non-triazine ultraviolet filters toward Chlorella vulgaris: Low ecological risk of triazine-based compounds.","journal":"Bioresource technology","published":"2026-07-27","design":"in_vitro","finding":"concern","summary":"Octocrylene exposure manifested delayed chronic toxicity driven by irreversible, intense oxidative damage in Chlorella vulgaris.","funding":"independent","conflictOfInterest":false,"fundingEvidence":["public: \"Natural Science Foundation\""],"fundingSource":"grant_metadata","verified":false},{"id":"pmid:42503170","pmid":"42503170","pmcid":"","doi":"10.1093/inteam/vjag121","title":"The applicability of New Approach Methodologies (NAMs) in aquatic hazard and risk assessments of cosmetic ingredients: a case study of UV filters.","journal":"Integrated environmental assessment and management","published":"2026-07-25","design":"other","finding":"mixed","summary":"New approach methodologies and in silico tools were evaluated to screen aquatic hazard and environmental risk for nine UV filters, including ethylhexyl methoxycinnamate.","funding":"unclear","conflictOfInterest":false,"fundingEvidence":[],"fundingSource":"none","verified":false},{"id":"pmid:42462094","pmid":"42462094","pmcid":"","doi":"10.1093/inteam/vjag112","title":"Organic UV Filter Exposure in Children of Indonesia, Thailand, and Saudi Arabia - Urinary Concentrations, Risks, and Potential Sources.","journal":"Integrated environmental assessment and management","published":"2026-07-15","design":"human_cross_sectional","finding":"no_effect","summary":"Urinary biomonitoring of 301 children in three countries found widespread octocrylene exposure linked to non-sunscreen sources, with metabolite levels below the HBM-I value.","funding":"unclear","conflictOfInterest":false,"fundingEvidence":[],"fundingSource":"none","verified":false},{"id":"pmid:42456500","pmid":"42456500","pmcid":"","doi":"10.1016/j.marpolbul.2026.120075","title":"High vulnerability of jellyfish ephyras (Aurelia aurita) and copepods (Calanoids) to understudied organic UV filters: A multi-trophic ecotoxicological assessment.","journal":"Marine pollution bulletin","published":"2026-07-15","design":"animal","finding":"concern","summary":"Octocrylene demonstrated acute toxicity in Artemia franciscana and caused pulsing behavioral issues in Aurelia aurita jellyfish ephyras.","funding":"unclear","conflictOfInterest":false,"fundingEvidence":[],"fundingSource":"none","verified":false},{"id":"pmid:42240897","pmid":"42240897","pmcid":"PMC13236757","doi":"10.1007/s10661-026-15437-4","title":"Application of LC-MS/MS methods and risk assessment for selected emerging contaminants and their transformation products in a sub-Adriatic river system.","journal":"Environmental monitoring and assessment","published":"2026-06-04","design":"other","finding":"no_effect","summary":"Octocrylene was detected in river water samples with higher abundance observed near wastewater treatment plants.","funding":"independent","conflictOfInterest":false,"fundingEvidence":["public: \"University\""],"fundingSource":"full_text","verified":false},{"id":"pmid:41712751","pmid":"41712751","pmcid":"","doi":"10.1093/etojnl/vgag047","title":"Probabilistic emissions model for organic UV filters released to recreational waters during swimming/bathing events.","journal":"Environmental toxicology and chemistry","published":"2026-06-01","design":"other","finding":"no_effect","summary":"A probabilistic kinetic model estimated the mass of organic UV filters, including oxybenzone, released into recreational waters from sunscreen during swimming events.","funding":"industry","conflictOfInterest":false,"fundingEvidence":["industry: \"Personal Care Products Council\""],"fundingSource":"grant_metadata","verified":false},{"id":"pmid:42173181","pmid":"42173181","pmcid":"","doi":"10.1016/j.cbpc.2026.110574","title":"Age-dependent modulation of CYP450 and MXR activity and physiological trade-offs in Daphnia magna exposed to organic UV filters.","journal":"Comparative biochemistry and physiology. Toxicology & pharmacology : CBP","published":"2026-05-21","design":"animal","finding":"concern","summary":"Exposure to UV filters including octocrylene caused age-dependent alterations in detoxification enzymes, antioxidant mobilization, and heart rate in Daphnia magna.","funding":"unclear","conflictOfInterest":false,"fundingEvidence":[],"fundingSource":"grant_metadata","verified":false},{"id":"pmid:42167390","pmid":"42167390","pmcid":"","doi":"10.1016/j.etap.2026.105047","title":"UV-protective agents threaten bivalve reproduction: Impacts of octocrylene and benzophenone on gamete quality and fertilization in the Pacific oyster (Magallana gigas).","journal":"Environmental toxicology and pharmacology","published":"2026-05-20","design":"in_vitro","finding":"concern","summary":"Ex vivo exposure to octocrylene and benzophenone induced spermiotoxicity via DNA damage and reduced fertilization success in Pacific oyster gametes.","funding":"unclear","conflictOfInterest":false,"fundingEvidence":[],"fundingSource":"grant_metadata","verified":false},{"id":"pmid:42197211","pmid":"42197211","pmcid":"PMC13209708","doi":"10.3390/molecules31101656","title":"Organic Sunscreens-Biological Activity from an Enzymatic Perspective.","journal":"Molecules (Basel, Switzerland)","published":"2026-05-14","design":"other","finding":"concern","summary":"Computational modeling identified octocrylene as likely to be a strong inhibitor of butyrylcholinesterase.","funding":"independent","conflictOfInterest":false,"fundingEvidence":["public: \"University of Lodz https://ror.org/02t4ekc95 503/3-016-03/503-31-001 This research study was supported by an internal grant\""],"fundingSource":"full_text","verified":false},{"id":"pmid:42064010","pmid":"42064010","pmcid":"PMC13125873","doi":"10.1155/jt/7171333","title":"Cellular and Systemic Toxicity Induced by Sunscreen and Paraben Mixtures and the Implications for Root Development in Cultivated Plants.","journal":"Journal of toxicology","published":"2026-04-28","design":"other","finding":"concern","summary":"Octocrylene in mixtures with methylparaben or butylparaben altered root development, induced cellular toxicity, and reduced root structural stability in cucumber, tomato, and onion.","funding":"independent","conflictOfInterest":false,"fundingEvidence":["public: \"Conselho Nacional de Desenvolvimento\""],"fundingSource":"full_text","verified":false},{"id":"pmid:42035406","pmid":"42035406","pmcid":"","doi":"10.1080/15287394.2026.2662562","title":"Ecotoxicological assessment of photo-ozonation applied to emerging contaminants in single and mixed systems: evidence of increased toxicity after treatment.","journal":"Journal of toxicology and environmental health. Part A","published":"2026-04-26","design":"animal","finding":"concern","summary":"Octocrylene, benzophenone, and their mixtures displayed mutagenic effects in Allium cepa, with increased cytotoxicity and mutagenicity observed following photo-ozonation treatment.","funding":"unclear","conflictOfInterest":false,"fundingEvidence":[],"fundingSource":"grant_metadata","verified":false},{"id":"pmid:41985167","pmid":"41985167","pmcid":"","doi":"10.1080/15569527.2026.2649261","title":"Leveraging a TRPV1-overexpressing cell model: an integrated testing strategy for UV filter-induced ocular irritation.","journal":"Cutaneous and ocular toxicology","published":"2026-04-15","design":"in_vitro","finding":"no_effect","summary":"Testing of ethylhexyl methoxycinnamate (octinoxate) showed it was nonirritating in BCOP and STE assays and did not activate TRPV1 channels in corneal epithelial cells.","funding":"unclear","conflictOfInterest":false,"fundingEvidence":[],"fundingSource":"none","verified":false},{"id":"pmid:41908471","pmid":"41908471","pmcid":"PMC13019394","doi":"10.1021/acsomega.5c12445","title":"Ultrafast Spectroscopy of Commercial Sunscreen Formulations in Thin Films and on a Skin Mimic.","journal":"ACS omega","published":"2026-03-11","design":"in_vitro","finding":"no_effect","summary":"Ultrafast laser spectroscopy showed the fundamental photodynamics of sunscreen formulations containing octocrylene and other UV filters are comparable in dilute solution, thin films, and skin mimics.","funding":"independent","conflictOfInterest":false,"fundingEvidence":["public: \"European Union\""],"fundingSource":"full_text","verified":false},{"id":"pmid:41697961","pmid":"41697961","pmcid":"","doi":"10.1093/inteam/vjag030","title":"Screening-level exposure Models to Evaluate the direct Release of Cosmetic Ingredients (MERCI): Development and application to UV filters used in suncare products.","journal":"Integrated environmental assessment and management","published":"2026-02-16","design":"other","finding":"no_effect","summary":"Screening-level models were developed and applied to estimate octocrylene concentrations in freshwater, marine water, and sediment resulting from sunscreen wash-off during outdoor recreational activities.","funding":"unclear","conflictOfInterest":false,"fundingEvidence":[],"fundingSource":"grant_metadata","verified":false},{"id":"pmid:41726609","pmid":"41726609","pmcid":"PMC12917627","doi":"10.1021/acsomega.5c09234","title":"<i>In Silico</i> Perspective on Avobenzone, Octisalate, Octocrylene, Homosalate, and Bemotrizinol as Organic UV Filters Using DFT, TD-DFT, and Molecular Dynamics.","journal":"ACS omega","published":"2026-02-02","design":"other","finding":"no_effect","summary":"Computational DFT and molecular dynamics simulations evaluated the electronic properties, absorption spectra, and solvent effects of organic UV filters, including octocrylene.","funding":"unclear","conflictOfInterest":false,"fundingEvidence":[],"fundingSource":"none","verified":false},{"id":"pmid:41518963","pmid":"41518963","pmcid":"","doi":"10.1016/j.marpolbul.2025.119195","title":"Occurrence of twelve UV filters and evidence of cis-octinoxate formation in Adriatic coastal waters: Environmental implications.","journal":"Marine pollution bulletin","published":"2026-01-09","design":"other","finding":"no_effect","summary":"4-Methylbenzylidene camphor was detected alongside other UV filters in seawater samples collected along the Adriatic coast during peak recreational activity.","funding":"independent","conflictOfInterest":false,"fundingEvidence":["public: \"Ministerio de\""],"fundingSource":"grant_metadata","verified":false},{"id":"pmid:41484732","pmid":"41484732","pmcid":"","doi":"10.1007/s12010-025-05524-6","title":"Hybrid Herbal-Synthetic Sunscreen Formulations: Boosting SPF With Hippophae Rhamnoides and Sapindus Mukorossi Extracts.","journal":"Applied biochemistry and biotechnology","published":"2026-01-03","design":"in_vitro","finding":"no_effect","summary":"Combining Hippophae rhamnoides or Sapindus mukorossi extracts with 5% octocrylene enhanced in vitro SPF and antioxidant activity while maintaining emulsion stability over 8 weeks.","funding":"unclear","conflictOfInterest":false,"fundingEvidence":[],"fundingSource":"none","verified":false},{"id":"pmid:41411795","pmid":"41411795","pmcid":"","doi":"10.1016/j.ecoenv.2025.119584","title":"Acute toxicity of novel triazine-based UV filters towards Chlorella vulgaris and Daphnia magna: Single and mixture effect.","journal":"Ecotoxicology and environmental safety","published":"2025-12-17","design":"animal","finding":"concern","summary":"Octocrylene induced concentration-dependent growth inhibition in Chlorella vulgaris and acute toxicity in Daphnia magna, exhibiting synergistic effects when combined with avobenzone and BEMT.","funding":"independent","conflictOfInterest":false,"fundingEvidence":["public: \"Ministry of\""],"fundingSource":"grant_metadata","verified":false},{"id":"pmid:41319926","pmid":"41319926","pmcid":"","doi":"10.1016/j.bcp.2025.117564","title":"Assessing the hepatic metabolism of six sunscreen ultraviolet filters: In vitro-in vivo extrapolation approach using human liver microsomes and hepatic parameter predictions for exposure risk assessment.","journal":"Biochemical pharmacology","published":"2025-11-28","design":"in_vitro","finding":"concern","summary":"In vitro testing with human liver microsomes showed octocrylene had relatively higher half-lives, suggesting potential for bioaccumulation.","funding":"unclear","conflictOfInterest":false,"fundingEvidence":[],"fundingSource":"grant_metadata","verified":false},{"id":"pmid:41271128","pmid":"41271128","pmcid":"","doi":"10.1016/j.envres.2025.123368","title":"Environmental occurrence, spatial distribution and risk assessment of ultraviolet filters in sediments from Liaodong Bay, Bohai Sea, China.","journal":"Environmental research","published":"2025-11-19","design":"other","finding":"no_effect","summary":"Octocrylene was detected in marine sediments from Liaodong Bay, China, with nearshore enrichment, but did not have risk quotient values exceeding one.","funding":"independent","conflictOfInterest":false,"fundingEvidence":["public: \"National Natural Science Foundation of China\""],"fundingSource":"grant_metadata","verified":false},{"id":"pmid:40713895","pmid":"40713895","pmcid":"","doi":"10.1093/etojnl/vgaf192","title":"Are standard test species still relevant? A comprehensive assessment of Daphnia pulex reared in laboratory and wild environments and their responses to organic ultraviolet filters.","journal":"Environmental toxicology and chemistry","published":"2025-11-01","design":"animal","finding":"concern","summary":"Exposure to octocrylene caused decreased reproduction and mortality in Daphnia pulex, with wild populations showing greater sensitivity in reproduction compared to laboratory populations.","funding":"independent","conflictOfInterest":false,"fundingEvidence":["public: \"Research Council\""],"fundingSource":"grant_metadata","verified":false},{"id":"pmid:41215685","pmid":"41215685","pmcid":"PMC12603680","doi":"10.1111/jocd.70538","title":"Innovative Safe Sunscreens Technology: Evaluation of Skin Penetration Through In Vitro/In Vivo Assays and Environmental Friendliness.","journal":"Journal of cosmetic dermatology","published":"2025-11-01","design":"other","finding":"mixed","summary":"Microencapsulating octocrylene and avobenzone prevented skin penetration and irritation compared to a conventional formulation while maintaining sun protection efficacy.","funding":"unclear","conflictOfInterest":false,"fundingEvidence":[],"fundingSource":"none","verified":false},{"id":"pmid:41307320","pmid":"41307320","pmcid":"","doi":"10.1093/inteam/vjaf153","title":"Environmental occurrence of octocrylene in marine and freshwater systems: a critical review.","journal":"Integrated environmental assessment and management","published":"2025-10-31","design":"systematic_review","finding":"no_effect","summary":"A systematic review collated measured environmental concentrations of octocrylene in marine and freshwater surface waters and sediments to evaluate exposure data reliability for risk assessments.","funding":"industry","conflictOfInterest":false,"fundingEvidence":["industry: \"Cosmetics Europe\""],"fundingSource":"grant_metadata","verified":false},{"id":"pmid:41175627","pmid":"41175627","pmcid":"","doi":"10.1016/j.chemosphere.2025.144748","title":"An automated high-throughput platform reveals chromatic phototactic disruption in Daphnia magna exposed to the UV filters benzophenone-3 and octocrylene.","journal":"Chemosphere","published":"2025-10-31","design":"animal","finding":"concern","summary":"Exposure to octocrylene increased negative phototaxis, decreased movement, and altered color preference in Daphnia magna.","funding":"independent","conflictOfInterest":false,"fundingEvidence":["public: \"Horizon Europe\""],"fundingSource":"grant_metadata","verified":false},{"id":"pmid:41192185","pmid":"41192185","pmcid":"","doi":"10.1016/j.jhazmat.2025.140323","title":"Subchronic exposure to four organic UV filters disrupted thyroid endocrine and neuronal systems in zebrafish: Insights into underlying toxicological mechanisms at different life stages.","journal":"Journal of hazardous materials","published":"2025-10-31","design":"animal","finding":"concern","summary":"Exposure to organic UV filters including octocrylene increased thyroid hormone levels and induced behavioral alterations along with neural gene expression changes in juvenile and adult zebrafish.","funding":"independent","conflictOfInterest":false,"fundingEvidence":["public: \"Ministry of\""],"fundingSource":"grant_metadata","verified":false},{"id":"pmid:41054931","pmid":"41054931","pmcid":"PMC13045768","doi":"10.1002/tox.24571","title":"Ecotoxicological Evaluation of Organic Sunscreens Used Worldwide, Alone and in Mixture, on Terrestrial Plants.","journal":"Environmental toxicology","published":"2025-10-07","design":"other","finding":"concern","summary":"Octocrylene alone and in mixtures induced phytotoxicity, cytotoxicity, and genotoxicity in Daucus carota, Solanum lycopersicum, and Allium cepa roots.","funding":"independent","conflictOfInterest":false,"fundingEvidence":["public: \"CAPES\""],"fundingSource":"full_text","verified":false},{"id":"pmid:41038028","pmid":"41038028","pmcid":"","doi":"10.1016/j.ecoenv.2025.119151","title":"Specific toxicity of octinoxate and octocrylene on Symbiodinium sp., a symbiotic microalga with corals.","journal":"Ecotoxicology and environmental safety","published":"2025-10-01","design":"in_vitro","finding":"concern","summary":"Exposure of Symbiodinium sp. to octocrylene altered cell complexity and lipid peroxidation, and reduced cell viability and metabolic activity at elevated concentrations.","funding":"unclear","conflictOfInterest":false,"fundingEvidence":[],"fundingSource":"grant_metadata","verified":false},{"id":"pmid:40953763","pmid":"40953763","pmcid":"","doi":"10.1016/j.cbpc.2025.110355","title":"Morphological, behavioral, and molecular neurotoxicity of octocrylene in zebrafish larvae.","journal":"Comparative biochemistry and physiology. Toxicology & pharmacology : CBP","published":"2025-09-13","design":"animal","finding":"concern","summary":"Exposure of zebrafish embryos to octocrylene impaired hatching and heart rate, reduced neural cell populations, altered behavior, and triggered brain apoptosis.","funding":"independent","conflictOfInterest":false,"fundingEvidence":["public: \"National Natural Science Foundation of China\""],"fundingSource":"grant_metadata","verified":false},{"id":"pmid:40834517","pmid":"40834517","pmcid":"","doi":"10.1016/j.scitotenv.2025.180258","title":"Assessing human exposure to organic UV filters through biomonitoring in South Korea.","journal":"The Science of the total environment","published":"2025-08-20","design":"human_cohort","finding":"no_effect","summary":"Biomonitoring of 124 South Korean family members detected octocrylene, its metabolite CDAA, and benzophenones in urine, showing significant seasonal variations with higher concentrations in summer.","funding":"unclear","conflictOfInterest":false,"fundingEvidence":[],"fundingSource":"grant_metadata","verified":false},{"id":"pmid:40754163","pmid":"40754163","pmcid":"","doi":"10.1016/j.envpol.2025.126934","title":"Getting over it? A proteomic analysis of mechanisms driving multigenerational acclimation to organic ultraviolet filters in Daphnia magna.","journal":"Environmental pollution (Barking, Essex : 1987)","published":"2025-08-05","design":"animal","finding":"mixed","summary":"Octocrylene exposure caused metabolic and immune proteomic impairments in F0 Daphnia magna, which gradually reversed by the F3 generation due to acclimation mechanisms.","funding":"independent","conflictOfInterest":false,"fundingEvidence":["public: \"Research Council\""],"fundingSource":"grant_metadata","verified":false},{"id":"pmid:40712201","pmid":"40712201","pmcid":"","doi":"10.1016/j.envpol.2025.126830","title":"Organic ultraviolet filters in the blubber of two free-ranging deep-diving cetacean species.","journal":"Environmental pollution (Barking, Essex : 1987)","published":"2025-07-24","design":"animal","finding":"no_effect","summary":"Octocrylene and three other organic UV filters were detected and quantified in the blubber of short-finned pilot whales and sperm whales off Madeira Island.","funding":"independent","conflictOfInterest":false,"fundingEvidence":["public: \"Fundação para a Ciência\""],"fundingSource":"grant_metadata","verified":false},{"id":"pmid:40651348","pmid":"40651348","pmcid":"","doi":"10.1016/j.marpolbul.2025.118403","title":"Hidden costs of beauty: An in vitro study on the ecotoxicological impacts of ultraviolet filters and parabens on the bioindicator species Mytilus galloprovincialis.","journal":"Marine pollution bulletin","published":"2025-07-11","design":"in_vitro","finding":"concern","summary":"In vitro exposure of Mytilus galloprovincialis S9 fractions to octocrylene triggered an increase in glutathione peroxidase activity.","funding":"independent","conflictOfInterest":false,"fundingEvidence":["public: \"European Commission\""],"fundingSource":"grant_metadata","verified":false}],"model":"gemini-3.8-flash","run":{"aiCalls":33,"cachedPapers":5,"offTopic":1,"inputTokens":21552,"outputTokens":4495}}